HomeProductsImagingElectrophysiology Motorized Micromanipulators
647_pcs-6000series
6478_pcs-6000series
pcs-6000_assembly_780
mech_stop_7808
t-cube_7806
pcs-6000_joystick_780
pcs-6000_powersupply_780
6480_pcs-6400tr_sgl
6481_pcs-6400tl_sgl
6482_pcs-6400cr_sgl
6483_pcs-6400cl_sgl

Motorized Micromanipulators

PrintEmail

Motorized Patch-Clamp Micromanipulators




  • Stepper Motor and Piezo Controlled Micromanipulator Assembly for Precision Control
  • Options for 150 or 300 µm of Piezo Travel
  • Ideal for Gibraltar Microscope Platforms

Features

  • Solid-State Stability of Piezoelectric Technology
  • Negligible drift,
  • Adjustable Set Stops Allow Easy Pipette Exchange
  • Stepper Motor Travel Range: 25.4 mm
  • Fine Control Optional Ranges: 150 or 300 µm (Minimum Resolution: 60 nm)

Thorlabs' PCS-6000 micromanipulator offers excellent control of pipette manipulation for electrophysiology research. Our micromanipulators use piezoelectric (PZT) control of translation stages to provide smooth and precise movement of the pipette head without inducing drift. The PCS-6000 micromanipulators provide superior performance compared to other standard control techniques. Hydraulic manipulators succumb to drift through fluid expansion, contraction, and leakage. Mechanical manipulators are not predictable on the scale necessary for electrophysiology research and can transmit fingertip vibrations to the pipette. Motorized lead screws may also lead to uncertainty through inconsistent motion and backlash in the screws.

The PZT control employed by our micromanipulators provide much smoother and predictable movement with no backlash and minimal drift (

Our motorized micromanipulators can use either a joystick or computer interface to control the stepper motor translation. Additionally, the user is able to store up to two independent positions in memory. Push button control on either control system (joystick or computer) recalls the stored position, allowing the user to quickly and easily move between two predetermined positions on the micromanipulator.

We offer our motorized micromanipulators in either a traditional configuration or a cultured configuration (see images below). For patching cultured cells, we offer the cultured configuration. Control over the 3 cardinal directions (X, Y, and Z) is the best. X and Y translation position the pipette over the cell of interest and then the Z translation brings the pipette down for patching. For applications such as brain slice work, we offer the traditional configuration. In these applications, the pipette moves to the slice at an approach angle and thus control over Y, Z, and Approach Axis translation is preferred.

 

SpecificationsPiezoMotorized
Travel 150 or 300 µm 25 mm
Resolution 1.6 µm (Min)
Speed Directly Proportional to Rate of Knob Turns Continuously Variable from .5 nm/s to 2 mm/s
Memory Speed 3.5 mm/s
Drift  
Computer Interface USB
Manipulator Dimensions (L×W×H) 7" × 8.5" × 7.5"
(178 mm x 216 mm x 190.5 mm)

 

 

Micromanipulator Assembly

Thorlabs’ Micromanipulator Assembly is composed of three linear translation stages, two rotary stages with lockable stops, one set of angle brackets, and headstage mounting plate. The cross roller bearings of this assembly form a stiff and precise single-axis bearing system with high load capacity and minimal friction. The PZT actuators yield 60 µm resolution, virtually no heating, zero backlash, and negligible drift (

The headstage mounting plate easily accommodates headstages and pipettes. Note that while many headstages may be directly bolted to the headstage mounting plate, other headstages may be mounted to the mounting plate by adding the appropriate mounting holes.

The headstage pivot allows for simple optimization of the pipette angle of approach on either an inverted or upright microscope. Additionally, the PCS-500-SSH Steep/Shallow Headstage Adapter may be used in applications requiring very steep or shallow angles. Due to the symmetric design of our micromanipulator assembly, this system can be easily modified to provide a left-sided or orthogonal approach axis without needing a special adapter kit.

Adjustable Set Stops

The headstage pivot allows any angle of approach for the pipette. The integrated adjustable stop mechanism allows for the approach angle to be repeatedly set with a high degree of reliably, giving the user a convenient mechanism to change out pipettes and quickly reset to the appropriate approach angle. Thorlabs’ micromanipulator assembly has two rotation plates, each with its own individual adjustable stop. The image to the left shows the adjustable stop mechanism for our rotation stages.

When the appropriate approach angle has been established, the stops can be set by loosening the setscrews of the locking ring and rotating the ring until the pin is in physical contact with the brass block. When both stops are set, the assembly can be rotated clear of the microscope to exchange pipettes and then quickly reset to the appropriate angle (see image above). This mechanism provides a quick and easy method to exchange pipettes and return to working condition, limiting the amount of time for position readjustmentsand increasing efficiency in collecting data.

 

Axis Control Unit

The axis control unit allows the user to adjust pipette placement by hand with smooth and repeatable movement through control of the piezo flexure mount. Each of the three stages that comprise our micromanipulator assembly can connect to one of the potentiometer knobs on the axis control unit. For convenience of system configuration, the user may choose any knob to control any particular stage. This allows the user to set the axis control unit in the most intuitive configuration for the system.

Each knob controls a three-turn potentiometer, which regulates voltage to the piezo flexure assembly and thus its position. Three turns on the potentiometer corresponds to full scale of the piezo assembly, yielding a resolution that is 0.04% of the total piezo travel range. For example, a 150 µm piezo travel stage will have a 60 nm resolution provided by the axis control unit. Additionally, the user may set the potentiometer friction to suit experimental needs.

Joystick and Computer Controller

Control of the stepper motors is accomplished through the use of either the Joystick or Computer. The computer control features a virtual joystick and gives 3-D position readouts. Both joystick and computer control allow the user to store up to two independent positions in memory and give simple push button recall to said positions. This allows the user to quickly and reliably switch between two preset positions. The joystick offers analog control allowing the motorized assembly speed to be controlled continuously between 0.5 nm/s to 2 mm/s (for computer control, this sensitivity can be directly set in the GUI) and offers a minimum step size of 1.6 µm.

Power Supply

Our micromanipulator power supply provides a regulated, low noise, 60 V output for the axis control unit. Two voltage outputs enable the power supply to regulate two axis control units. This allows the user to run two micromanipulation assemblies from the same power source, saving both money and space. This power supply accepts an input power range of 100 – 240 V at 50/60 Hz.

 


Right-Handed, Traditional Micromanipulator

 

ModelY-Axis*Z-Axis*Approach-Axis*Comments/Applications
PCS-6200TR 150 µm 150 µm 150 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on each stage
PCS-6300TR 150 µm 150 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on X and Z axis, 300 µm of PZT Travel on Approach axis.
PCS-6400TR 300 µm 300 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
300 µm of PZT travel on each stage

*Piezo Travel Range

 

Left-Handed, Traditional Micromanipulator

 

ModelY-Axis*Z-Axis*Approach-Axis*Comments/Applications
PCS-6200TL 150 µm 150 µm 150 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on each stage
PCS-6300TL 150 µm 150 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on X and Z axis, 300 µm of PZT Travel on Approach axis.
PCS-6400TL 300 µm 300 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
300 µm of PZT travel on each stage

*Piezo Travel Range

 

Right-Handed, Cultured Micromanipulator

 

ModelX-Axis*Y-Axis*Z-Axis*Comments/Applications
PCS-6200CR 150 µm 150 µm 150 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on each stage
PCS-6300CR 150 µm 150 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on X and Y axis, 300 µm of PZT Travel on Z axis.
PCS-6400CR 300 µm 300 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
300 µm of PZT travel on each stage

*Piezo Travel Range

 

Left-Handed, Cultured Micromanipulator

 

ModelX-Axis*Y-Axis*Z-Axis*Comments/Applications
PCS-6200CL 150 µm 150 µm 150 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on each stage
PCS-6300CL 150 µm 150 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
150 µm of PZT travel on X and Y axis, 300 µm of PZT Travel on Z axis.
PCS-6400CL 300 µm 300 µm 300 µm Three-axis motorized stages with 25 mm of travel of motorized Travel.
300 µm of PZT travel on each stage

*Piezo Travel Range

ABOUT US

Our Mission is to accelerate the advancement of optical technology for precision measurements and their applications from the table tops of research laboratories to standard use in communication and high technology industries. Our aim is to serve our customers. Our hope is to create a place for highly skilled people in an open environment

contact us

Tel               +966 35823441
Fax               +966 35823441
Egypt Mobile  +2 0120 7577664
KSA Mobile     +966 545 991188
Email             This email address is being protected from spambots. You need JavaScript enabled to view it.

newsletter